When you need both blister protection and insulation from the elements then look to the Wrightsock Cold Weather Sock for the answer.
Wrightsock's Double Layer Anti-Blister run sock with insulating ThermaStat in place of Dri-Wright. ThermaStat is a hollow core polyester designed to trap air inside the fiber as an insulator to the outside cold elements.
Flat knit (non cushion) mid-weight design. Less bulk doesn't compromise shoe fit.
Seamless toe reduces abrasions.
Great design and a deep heel gore ensures the fit is perfect during your entire run.